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Image Search Results
Journal: Heliyon
Article Title: Pharmacological investigation of taxifolin for its therapeutic potential in depression
doi: 10.1016/j.heliyon.2024.e30467
Figure Lengend Snippet: The best conformational pose, binding energy (kcal/mol), number of hydrogen bonds, bonding residues forming other hydrophobic interactions, of taxifolin and fluoxetine with target proteins such as peroxisome proliferator-activated receptor gamma (PPAR-γ), cyclooxygenase-2 (COX-2), Toll like receptor-4 (TLR4), c-Jun N-terminal kinase (JNK), brain-derived neurotrophic factor (BDNF), monoamine oxidase A (MAO-A), heme oxygenase-1 (HO-1), cyclooxygenase-1 (COX-1), sodium channels (NA+),Glutamate receptor (GRM2), phosphoinositide 3-kinase (PI3k), tumor necrosis factor-alpha (TNF-α), prostaglandins (PGE2), mitogen activated protein kinases (MAPK), Beta- 2 adrenergic receptor (ADRB2), Neurokinin receptor (NK-1), Procaspase activating compound (PAC-1), nuclear factor kappa B (NF-κB), nitric oxidase synthesis (iNOS), interleukin-4 (IL-4), high mobility group box 1 (HMGB1), Protein -c –fos, Beta catenin (β-Catenin), serotonin receptors (SERT), nuclear factor erythroid 2-related factor 2 (Nrf2), vasoactive intestinal peptide (VIP), Gamma-aminobutyric acid (GABA A), peptidoglycan (PG), interleukin-2 (IL-2), Dopamine receptor (D2).
Article Snippet: The ELISA kit COX-2 (CAT# PRS-30205Ra) and the
Techniques: Binding Assay
Journal: Heliyon
Article Title: Pharmacological investigation of taxifolin for its therapeutic potential in depression
doi: 10.1016/j.heliyon.2024.e30467
Figure Lengend Snippet: Effects of Taxifolin and Fluoxetine against (A) Peroxisomes proliferation-activated receptor-γ (PPAR-γ) and (B) Cyclooxygenase-2 (COX-2) concentration in rat's cortex tissues using enzyme linked immunosorbent assay technique (ELISA). Values expressed as mean ± SEM (n = 6). One-way ANOVA with post hoc Tukey’ s test. ### P < 0.001 vs. saline group, *P < 0.05, **P < 0.01, ***P < 0.001 vs. LPS group.
Article Snippet: The ELISA kit COX-2 (CAT# PRS-30205Ra) and the
Techniques: Concentration Assay, Enzyme-linked Immunosorbent Assay, Saline
Journal: Heliyon
Article Title: Pharmacological investigation of taxifolin for its therapeutic potential in depression
doi: 10.1016/j.heliyon.2024.e30467
Figure Lengend Snippet: Effects of Taxifolin and Fluoxetine against Peroxisomes proliferation-activated receptor-γ (PPAR-γ) by RT-PCR. Values expressed as mean ± SEM (n = 6). One-way ANOVA with post hoc Tukey’ s test. ### P < 0.001 vs saline group, **P < 0.01, ***P < 0.001 vs. LPS group.
Article Snippet: The ELISA kit COX-2 (CAT# PRS-30205Ra) and the
Techniques: Reverse Transcription Polymerase Chain Reaction, Saline